Postdoctoral Associate position in Microfluidic / Cancer Bioengineering
Microenvironment Engineering Laboratory
University of Pittsburgh, Department of Bioengineering and UPMC Cancer Center
A postdoctoral position is available at the Microenvironment Engineering lab in the Department of Bioengineering and UPMC Cancer Institute. We employ a quantitative approach that integrates microfluidics, systems biology modeling, and in vivo experiments to investigate the role of the normal and diseased microenvironment on tissue fibrosis, breast and ovarian cancer growth, metastasis, and drug resistance. Our group has projects in three main areas: (1) Macrophage interactions with fibroblasts in tissue homeostasis/healing/fibrosis using single-cell and 3D ECM functional assays under microenvironmental control (e.g., hypoxia). (2) Metastatic dissemination and mechanotransduction in ovarian cancer. (3) Drug-resistant microenvironments: analysis of cellular stress, and cell-cell interaction dynamics.
Applicants should hold a PhD in bioengineering, biomedical sciences, engineering sciences, or related fields. We are seeking candidates with a quantitative background and/or experience with mechanistic biological studies. Hybrid wet/dry lab projects are also possible for candidates with expertise in mechanistic modeling and systems analysis (computational/statistical/bioinformatic approaches).
The Microenvironment Engineering laboratory offers the opportunity to work at the forefront of cancer bioengineering, learn cutting-edge techniques, and collaborate with an interdisciplinary group of scientists and clinicians. The candidate will benefit from the rich biomedical research environment at the University of Pittsburgh, including the UPMC Hillman Cancer Center, the Department of Computational and Systems Biology, the Drug Discovery Institute, and the Magee Women's Research Institute. The city of Pittsburgh is one of the "most livable" cities in the US and is a leader in medicine, engineering, and high-tech industries.
Please visit the website (www.zervalab.com) to find out more about research projects, publications, mentoring, and collaborations. Interested applicants must submit a CV, statement of research interests, and contact information for three references with their application.
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